- What is polypeptide? It is a kind of compound whose molecular structure is between amino acid and protein.
- The polypeptides are divided into the following five types:
- Shengnuo Biotechnology is a high-tech China polypeptide manufacturers,who has over 19 years experience for the biotechnology .Our Products involve peptide raw materials,polypeptide drug.
What is polypeptide? It is a kind of compound whose molecular structure is between amino acid and protein.
It is composed of amino acids, but different from protein, it belongs to the intermediate substance between them. A compound in which amino acids can be linked to each other by peptide bonds is called a peptide. A peptide containing less than 10 amino acids is called an oligopeptide, and a peptide containing more than 50 amino acids is called a protein. Peptide has high biological activity, which can regulate various physiological activities and biochemical reactions. Up to now, more than 100 kinds of peptides have been found and isolated from human body. The research and utilization of peptides has been an unprecedented prosperity in the world.
The polypeptides are divided into the following five types:
- Cytokine mimic peptide
In recent years, it has become a hot topic to screen cytokine mimic peptides from peptide library by using known cytokine receptors. The mimic peptides of many growth factors, such as human erythropoietin, human thrombopoietin, human growth hormone, human nerve growth factor and interleukin, have been screened abroad. The amino acid sequence of these mimic peptides is different from that of their corresponding cytokines, but they have the activity of cytokines and have the advantage of small molecular weight. These cytokines mimic peptides are in the preclinical or clinical research stage.
- Antibacterial active peptide
When insects are stimulated by the external environment, they produce a large number of cationic peptides with antibacterial activity. More than 100 kinds of antimicrobial peptides have been screened out. In vitro and in vivo experiments have proved that many antimicrobial peptides not only have strong bactericidal ability but also kill tumor cells. For example, antimicrobial peptide D screened from silkworm shows a good application prospect and can be produced by genetic engineering technology. There are also many kinds of active peptides in snake venom. A small peptide of 13 amino acids (inkaialakkll) was isolated from snake venom, which has strong bactericidal ability to G + and G-bacteria.
- Peptides for cardiovascular diseases
Many plant traditional Chinese medicines have the functions of lowering blood pressure, blood lipid and hemolytic thrombus, which can not only be used as medicine, but also as health food. However, due to its active components can not be determined. Its application is very limited. It has been found that many active components are small molecular peptides. For example, the active peptides extracted by Chinese scientists from soybean can be directly absorbed through the small intestine, which can prevent and treat thrombosis, hypertension and hyperlipidemia, delay aging and improve the anti-tumor ability of the body. Many small peptides for cardiovascular diseases were also isolated from ginseng, tea, ginkgo leaves and other plants.
- Other small medicinal peptides
Small peptide drugs have made great progress in these aspects, but also in many other areas. For example, Sternberg found that a synthetic peptide (TP508) can promote the regeneration of wound blood vessels and accelerate the healing of deep wounds. Pfister et al. Found that a small peptide (RTR) 4 can prevent the infiltration of corneal inflammatory cells damaged by alkali and inhibit the inflammatory response. Carron et al. Confirmed that the two synthetic peptides screened could inhibit the resorption of osteoclasts to bone.
- Diagnostic peptides
The main use of polypeptide in diagnostic reagents is to detect antibodies against viruses, cells, mycoplasma, spirochetes and other microorganisms, cysticercosis, Trypanosoma and other parasites. Polypeptide antigens are more specific than natural microorganisms or parasite protein antigens, and are easy to prepare. Therefore, the false negative rate and background reaction of the assembled detection reagents are very low, which are easy to be used in clinic Use. Now the antibody detection reagents assembled with polypeptide antigens include: A, B, C, g or liver virus, HIV, human cytomegalovirus, herpes simplex virus, rubella virus, Treponema pallidum, cysticercosis, Trypanosoma, Lyme disease and rheumatoid. Most of the polypeptide antigens used are obtained from the natural protein analysis of the corresponding pathogenic body, and some are new small peptides screened from the peptide library.
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How many companies are there in peptide api manufacturer in china? The peptide api market is very promising, and the world is encouraging the development of peptide business. There is a peptide api list on the website Biofda.com, which contains various specifications of peptide APIs for customers to choose from. Shengnuo Technology is a peptide api manufacturer located in Chengdu, a city in southwest China. Not only peptide APIs, but also carnosine custom suppliers and cosmetic peptide suppliers
are many peptide apis manufacture in China, but they are all small-scale companies. The China peptide company such as Sinotech is a leading company in China and has a very high position.
As a Chinese peptide company, Sinotech has been working silently, hoping to become a top peptide company in the world. There are many countries producing peptides in the world, such as bulk drug substance in India, gmp custom peptide in uk, and peptide production in usa. So what is polypeptide? What kind of peptide synthesis supplier should you choose? Follow our website: www.biofda.com, here will tell you the answer.