Oligopeptide-10 (oligopeptide-10)-is an antibacterial peptide used to treat acne symptoms

Oligopeptide-10 (oligopeptide-10)-is an antibacterial peptide used to treat acne symptoms. ​Research data showed that the peptide showed excellent activity against P-acne bacteria alone, but it was found to be more effective in combination with low levels of salicylic acid. Salicylic acid can open the pores to allow oxygen to enter, while allowing oligopeptide-10 to enter the pores for maximum performance without irritation. Compared with the leading benzoyl peroxide brand, the 0.5% combination of oligopeptide 10 and 0.5% salicylic acid showed a 40% reduction in acne, irritation, pustules and papules after 28 days.

Oligopeptide-5 is prepared by recombinant expression in the prokaryotic expression system (E.coli). It is a non-glycosylated polypeptide composed of 169 amino acid residues and has a molecular weight of 19.2kDa.

Specific binding with the receptor KGFR to exert its multiple biological functions: participate in the development of tissues and organs; participate in the damage and repair of skin, stomach, intestine, kidney, bladder, lung and other epithelial cells; reduce side effects caused by radiotherapy and chemotherapy , With damage protection function. Product indicators:

Sensory indicators: Appearance: White flocs Odor: No peculiar smell Physical and chemical indicators: Biological activity: Mouse BALB/c 3T3 cell dose-dependent proliferation test ED50 is less than 2 ng/ml, the corresponding specific activity is 1.0x 105 IU /mg. Purity: The purity is greater than 95.0% determined by the following methods: (a) High performance liquid chromatography (SEC-HPLC); (b) Reduction and non-reduction SDS-PAGE, silver staining. Endotoxin residue: ≤5EU/mg (limulus reagent method).