What are those dry skin care peptides that you don’t know?

Nearly the term “beauty peptide” is highly sought after by the majority of women who love beauty. When buying and using it blindly, you will naturally ask what is a “beauty peptide”? Today, I will take you to the root cause.

What is a peptide?

Everyone knows that protein is the main bearer of life activities, amino acids are the basic unit of Pro, and peptides are the constituent fragments of protein structure, with a molecular weight between amino acid and protein.

What is a peptide?

Usually a compound composed of three or more amino acid molecules connected by peptide bonds is called a polypeptide. Among them, peptides composed of 2-10 amino acids are called oligopeptides (also called small molecule peptides) and are often used in cosmetics.

The three peptides, five peptides, and even nine peptides and other beauty peptides and beauty peptides commonly referred to in cosmetics are actually oligopeptides.

As early as the 1990s, cosmetics with natural proteins became popular. However, due to the unique physiological barrier properties of the stratum corneum of human skin, these macromolecular active ingredients are difficult to be absorbed through the epidermis. It was not until later that protein fragments-peptides were discovered, which are non-toxic, highly active, easy to absorb, specific biochemical and physiological mechanisms, and homologous to the body’s substances, which can essentially improve a series of skin problems, and then set off peptides. The boom in beauty and skin care products.

Naturally, some people will ask, since protein is difficult to absorb from the skin, and amino acids are small molecules, why are beauty peptides selling well?

One is that peptides are absorbed more quickly than amino acids; the other is that peptides are components originally present in the human body; the third is active absorption, while amino acids are passively absorbed; the fourth is low consumption. Compared with amino acids, peptide absorption has the characteristics of low or no energy consumption. ; Fifth, peptides are absorbed by the skin in a complete form; sixth, the absorption of peptides is more unsaturated than amino acids; seventh, there are many types of peptides, which use amino acids as substrates, and there are only 20 kinds of amino acids, which have countable functions.

Let’s understand what peptides are used in big-name cosmetics and what are their effects?

Peptide is the basic material that constitutes all cells of the human body, and it is the form of life. Beauty beauty is the most important theme of skin care products.

Because beauty peptides are non-toxic, highly active, easy to absorb, and can improve the skin’s special physiological activity, they are widely used in internationally renowned brands of skin care products. SK-Ⅱ, Estee Lauder, Chanel, Audi, Olay, Avon, Lancome, L’Oreal, etc. Generally speaking, tripeptides and pentapeptides can help promote collagen production;

tetrapeptides help anti-inflammatory and antioxidant; hexapeptides can prevent the release of neurotransmitters, similar to the effect of botulinum toxin. According to statistics, the most frequently used beauty peptide products by famous foreign brands are: glutathione, palmitoyl pentapeptide-3, acetyl hexapeptide-3, acetyl tetrapeptide-5, palmitoyl oligopeptide (palmitoyl oligopeptide) Acyl tripeptide-1), palmitoyl tetrapeptide-3 and carnosine, etc.

Whitening and freckle functional peptides

Water retention and moisturizing

The new tripeptide Syn-Hycan can promote the production and synthesis of hyaluronic acid in the epidermis. Hyaluronic acid in the epidermal layer can rebuild the extracellular space between keratinocytes, enable smooth nutrient exchange, and function as a ligand for signal transmission. It is an excellent moisturizer. In addition, the extracellular matrix (ECM) of the dermis of the skin is mainly composed of hyaluronic acid and collagen. The hyaluronic acid produced by the dermis supports structural proteins and skin cells, acts like a cushion, and retains moisture in the skin.

Syn-Hycan not only promotes the synthesis of hyaluronic acid, but also stimulates the production of stronger collagen, and its effect exerts a synergistic effect on the water retention of connective tissues.

Promote the growth of eyebrows, eyelashes and hair

Myristoyl pentapeptide-17 and myristoyl hexapeptide-16 activate keratin genes and promote the thickening and growth of eyelashes.

Eye bags

Acetyltetrapeptide-5 and dipeptide-2 are effective angiotensin converting enzyme (ACE) inhibitors, which can improve blood circulation by inhibiting the conversion of angiotensin I to angiotensin II.

Promote dermal repair

Palmitoyl hexapeptide-6, a peptide developed with genetic immune peptide as a template, can effectively stimulate fibroblast proliferation, collagen synthesis and cell migration.

Weight loss and slimming

Acetyl hexapeptide-39 inhibits the expression of PGC-1α (peroxisome proliferation-activated receptor γ co-activator-1α) and reduces the differentiation and maturation rate of adipocytes, thereby slowing down the accumulation of fat under the epidermis, achieving weight loss and body beauty Effect.

Breast enhancement

Acetyl hexapeptide-38 (Adifylinetm) is a new cosmetic peptide material developed by Marta and others of LipotecS.A in Spain, which can activate PGC-1α (closely related to the differentiation of adipocytes and their physiological functions). Regulate the rate of fat production, stimulate white fat cells to accumulate triglycerides and cholesteryl esters (oil droplets), promote the production rate of breast fat, and promote and support the secretion of collagen cells and other cells to change the volume of the human body. Large, can effectively prevent changes in body shape due to aging, thus showing a concave and convex body curve.

Smoothes wrinkles

Acetylhexapeptide-3, the new anti-wrinkle favorite Akirelin in the United States, Korea, France, Taiwan and other regions, can inhibit the synthesis of SNARE receptors, inhibit the excessive release of catecholamines and acetylcholine in the skin, and locally block neurotransmission The muscle contraction information affects the nerve conduction of the skin capsule, relaxes the facial muscles, and achieves the purpose of smoothing dynamic lines, static lines and fine lines. It is a safer, cheaper and milder botox cosmetic substitute. It can be added to cosmetic formulas in the form of lotions, gels, etc., which can achieve the ideal effect of removing wrinkles around the corners of the eyes, face and forehead.

Palmitoyl Tripeptide-5 (Collagen Peptide) is the most widely used cosmetic small molecule peptide. It has a hydrophilic peptide segment and a hydrophobic palmitoyl end. It has a strong ability to bind to cells and can pass through tissue growth factor (TGF). -β) Imitates the human body’s own mechanism, stimulates the synthesis of collagen and glucosamine in human fibroblasts, strengthens connective tissue, increases skin firmness, and significantly reduces facial wrinkles. It is mainly used in facial, eye and neck care product.

Anti-inflammatory and anti-aging

The p55PIK specific inhibitor is a subtype of PI3K (phosphatidylinositol-3-kinase) family. It is a derivative of a polypeptide sequence composed of 1-25 amino acid residues. It inhibits the proliferation of inflammatory cells and inhibits the development of inflammation during inflammation.

The activation of important NF-κB reduces the production and secretion of a variety of inflammatory factors, repairs damaged cells, has anti-inflammatory and soothing effects, and has no obvious side effects. At the same time, by interacting with specific protein phosphorylation kinases, it invades and transfers senescence factors, hinders their transmembrane signal transmission, regulates epidermal proliferation and differentiation, inhibits abnormal epithelial cell proliferation, normalizes the skin keratinization process, and changes new and dying cells Proportion of the relationship between collagen and hyaluronic acid to promote the supplement of nutrients such as collagen and hyaluronic acid into the dermis, play an anti-aging and firming effect.

Know the effects of common peptides in cosmetics, or are you curious about how they should be combined to achieve significant mild and non-irritating effects?

Take a new generation of improved targeting protein p55PIK specific inhibitor with anti-inflammatory and anti-aging activity peptides as an example. It combines pure and crystal clear active yeast fermentation product filtrate essence, rich in protein, vitamin B, minerals, immune polysaccharides, etc. There are more than 50 kinds of natural nutrients in the four categories, and contain a variety of biologically active substances, which will produce synergistic effects, higher activity, more controllable action sites, can clean pores, improve skin blood circulation and metabolism, and repair Fine lines and dry lines, firm and smooth skin, comb the skin lines, effectively eliminate swelling, improve facial relaxation; at the same time, it produces strong antioxidant properties that can help the skin resist free radical damage, prevent skin surface damage, tighten and anti-aging, Anti-inflammatory repair.

Speaking of this, you will know why beauty peptides are so powerful.