Chengdu Kaijie bio medicine Peptide API
CJC-1295 Product description
CJC-1295 is a synthetic peptide derivative of growth hormone-releasing hormone (GHRH).
Unlike CJC-1295-DAC, CJC-1295 does not contain a drug affinity complex (DAC) moiety and has a shorter half-life than the DAC-conjugated version in the blood.
CJC-1295 increases the secretion of growth hormone in primary rat anterior pituitary cells when used from picomolar to micromolar concentrations and into rat blood when administered subcutaneously at a dose of 1 µmol/kg.
CJC-1295 Chemical Properties
| Formal Name |
| L-tyrosyl-D-alanyl-L-α-aspartyl-L-alanyl-L-isoleucyl-L-phenylalanyl-L-threonyl-L-glutaminyl-L-seryl-L-tyrosyl-L-arginyl-L-lysyl-L-valyl-L-leucyl-L-alanyl-L-glutaminyl-L-leucyl-L-seryl-L-alanyl-L-arginyl-L-lysyl-L-leucyl-L-leucyl-L-glutaminyl-L-α-aspartyl-L-isoleucyl-L-leucyl-L-seryl-L-argininamide |
| CAS Number |
| 446036-97-1 |
| Synonyms |
| Modified GRF (1-29) |
| CJC-1295-no DAC |
| GHRH (1-29)-NH2 |
| Molecular Formula |
| C152H252N44O42 |
| Formula Weight |
| 3367.9 |
| Purity |
| ≥95% |
| Formulation |
| A crystalline solid |
| SMILES |
| NC([C@@H](NC([C@@H](NC([C@H](CC(C)C)NC([C@]([H])([C@H](CC)C)NC([C@@H](NC([C@@H](NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@@H](NC([C@@H](NC([C@H](C)NC([C@@H](NC([C@H](CC(C)C)NC([C@@H](NC([C@H](C)NC([C@H](CC(C)C)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@]([H])(NC([C@H](CC1=CC=CC=C1)NC([C@]([H])([C@H](CC)C)NC([C@H](C)NC([C@@H](NC([C@@H](C)NC([C@@H](N)CC2=CC=C(C=C2)O)=O)=O)CC(O)=O)=O)=O)=O)=O)[C@@H](C)O)=O)CCC(N)=O)=O)CO)=O)CC3=CC=C(C=C3)O)=O)CCCNC(N)=N)=O)CCCCN)=O)C(C)C)=O)=O)=O)CCC(N)=O)=O)=O)CO)=O)=O)CCCNC(N)=N)=O)CCCCN)=O)=O)=O)CCC(N)=O)=O)CC(O)=O)=O)=O)=O)CO)=O)CCCNC(N)=N)=O |
| InChi Code |
| InChI=1S/C152H252N44O42/c1-22-79(15)118(194-125(214)84(20)171-135(224)107(68-115(206)207)181-124(213)81(17)169-126(215)91(155)65-87-41-45-89(201)46-42-87)147(236)189-106(66-86-34-25-24-26-35-86)141(230)196-120(85(21)200)149(238)180-99(51-54-114(158)205)132(221)190-111(72-199)145(234)185-105(67-88-43-47-90(202)48-44-88)140(229)178-96(40-33-59-168-152(164)165)128(217)177-94(37-28-30-56-154)133(222)193-117(78(13)14)146(235)187-100(60-73(3)4)134(223)170-82(18)123(212)175-97(49-52-112(156)203)130(219)183-103(63-76(9)10)138(227)191-109(70-197)143(232)172-83(19)122(211)174-95(39-32-58-167-151(162)163)127(216)176-93(36-27-29-55-153)129(218)182-102(62-75(7)8)137(226)184-101(61-74(5)6)136(225)179-98(50-53-113(157)204)131(220)186-108(69-116(208)209)142(231)195-119(80(16)23-2)148(237)188-104(64-77(11)12)139(228)192-110(71-198)144(233)173-92(121(159)210)38-31-57-166-150(160)161/h24-26,34-35,41-48,73-85,91-111,117-120,197-202H,22-23,27-33,36-40,49-72,153-155H2,1-21H3,(H2,156,203)(H2,157,204)(H2,158,205)(H2,159,210)(H,169,215)(H,170,223)(H,171,224)(H,172,232)(H,173,233)(H,174,211)(H,175,212)(H,176,216)(H,177,217)(H,178,229)(H,179,225)(H,180,238)(H,181,213)(H,182,218)(H,183,219)(H,184,226)(H,185,234)(H,186,220)(H,187,235)(H,188,237)(H,189,236)(H,190,221)(H,191,227)(H,192,228)(H,193,222)(H,194,214)(H,195,231)(H,196,230)(H,206,207)(H,208,209)(H4,160,161,166)(H4,162,163,167)(H4,164,165,168)/t79-,80-,81+,82-,83-,84-,85+,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,117-,118-,119-,120-/m0/s1 |
| InChi Key |
| XOZMWINMZMMOBR-HRDSVTNWSA-N |
| Shipping & Storage Information |
| Storage |
| -20°C |
| Shipping |
| Wet ice in continental US; may vary elsewhere |
| Stability |
| ≥ 2 years |
Polypeptide Production Specifications
| CAS Registry Number | 128270-60-0 |
|---|---|
| Categories | APIsPeptides; Biopharmaceuticals |
| Sales markets | Western Europe; Asia; North America; Central/South America |
| Supplied from | China |
| Selling Points | International Approvals/Standards |
CPhIonline Consultation details
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