Semaglutide
Semaglutide (trade names Rybelsus, Ozempic) is a medication used for the treatment of type 2 diabetes.[1][2]
Semaglutide acts like human glucagon-like peptide-1 (GLP-1) so that it increases insulin secretion, thereby increasing sugar metabolism. It is distributed as a metered subcutaneous injection in a prefilled pen. One of its advantages over other antidiabetic drugs is that it has a long duration of action, thus, only once-a-week injection is sufficient.[3]
An injection version was approved in 2017 in the United States, and in Europe, Canada, and Japan in 2018. A version which is taken by mouth was approved in 2019 in the United States. It is the first glucagon-like peptide (GLP-1) receptor protein treatment approved for use in the United States that does not need to be injected.[4] It was developed by the Danish company Novo Nordisk.
Side effects including nausea, vomiting, diarrhea, abdominal pain, and constipation may occur.[5]
Semaglutide Specifications
| Synthesis mode | chemic synthesis，solid phase synthesis |
|---|---|
| Categories | APIsPeptides; Biopharmaceuticals |
| Sales markets | Western Europe; Asia; North America; Central/South America |
| Supplied from | China |
| Selling Points | International Approvals/Standards |
Show more specifications
Research Peptide APIs for Regulatory Market Peptide Bulk Drug
| Research Peptide APIs for Regulatory Market | |
|---|---|
| Product Name | US-DMF Time Point |
| Linaclotide | Before the end of 2019 |
| Ganirelix | Before the end of 2019 |
| Degarelix | Before the end of 2020 |
| Exenatide | Before the end of 2021 |
| Teduglutide | Before the end of 2021 |
| Cetrorelix | Before the end of 2021 |
| Semaglutide | Before the end of 2022 |
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