Somatostatin
Somatostatin, also known as growth hormone-inhibiting hormone (GHIH) or by several other names, is a peptide hormone that regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G protein-coupled somatostatin receptors and inhibition of the release of numerous secondary hormones. Somatostatin inhibits insulin and glucagon secretion.
Somatostatin has two active forms produced by the alternative cleavage of a single preproprotein: one consisting of 14 amino acids (shown in infobox to right), the other consisting of 28 amino acids.
Among the vertebrates, there exist six different somatostatin genes that have been named SS1, SS2, SS3, SS4, SS5 and SS6.Zebrafish have all six.The six different genes, along with the five different somatostatin receptors, allow somatostatin to possess a large range of functions.[9] Humans have only one somatostatin gene, SST.
Sequence: ala Gly Cys Lys ASN Phe Phe Trp Lys thr Phe thr ser Cys oh
Somatostatin Specifications
| Synthesis mode | chemic synthesis，solid phase synthesis |
|---|---|
| Categories | APIsPeptides; Biopharmaceuticals |
| Sales markets | Western Europe; Asia; North America; Central/South America |
| Supplied from | China |
| Selling Points | International Approvals/Standards |
Other Polypeptide APIs
| Chinese cGMP APIs | ||
|---|---|---|
| Product Name | GMP Certificate No. | WC |
| Levosimendan | SC20120022 | |
| Thymosin alpha1 | SC20140047 | |
| Enfuvirtide | SC20140098 | |
| Octreotide Acetate | SC20150121 | YES |
| Somatostatin | SC20150121 | |
| Thymopentin | SC20150121 | |
| Carbetocin | SC20160013 | |
| Atosiban | SC20170065 |
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