Bivalirudin Product description
CAS No.: 128270-60-0
Molecular formula: c98h138n24o33
English synonyms: 128270-60-0; L-leucine, d-phenylalanyl-l-pro-lyl-l-l-arginyl-l-l-pro-lylycycycycycycycyl-l-l-asparacyl-l-l-asparacyl-l-l-phenylalanyl-l-l-phenylalanyl-l-l-l-l-phenylalanyl-l-l-l-phenylalanyl-l-l-l-phenylalanyl-l-pro-lyl-l-l-l-l-phenylalanyl-l-l-l-l-l-arginyl-l-l-l-l-l-l-l-l-l-l-l-l-l-l-l-l-l-l-l-l-l-l-l-l-l l-tyrosyl -; D-phenylalanyl-L-prolyl-L-arginyl-L-prolylglycylglycylglycylglycyl-L-asparaginylglycyl-L-alpha-aspartyl-L-phenylalanyl-L-alpha-glutamyl-L-alpha-glutamyl-L-isoleucyl-L-prolyl-L-alpha-glutamyl-L-alpha-glutamyl-L-tyrosyl-L-leucine
Molecular weight: 2180.2853
Use as an anticoagulant in patients with unstable angina undergoing percutaneous transluminal coronary angioplasty .
Bivalirudin is a synthetic 20 residue peptide (thrombin inhibitor) which reversibly inhibits thrombin. Once bound to the active site, thrombin cannot activate fibrinogen into fibrin, the crucial step in the formation of thrombus. It is administered intravenously.
Because it can cause blood stagnation, it is important to monitor changes in hematocrit, activated partial thromboplastin time, international normalized ratio and blood pressure.
|CAS Registry Number||128270-60-0|
|Sales markets||Western Europe; Asia; North America; Central/South America|
|Selling Points||International Approvals/Standards|
Other Polypeptide APIs
|US-DMF LIST–Polypeptide APIs|
|Product Name||US-DMF No.||WC|
|Icatibant Acetate||DMF 28496||YES|
|Octreotide Acetate||DMF 30249||YES|
|Teriparatide Acetate||DMF 32144|
|Ziconotide Acetate||DMF 33139|
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