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Bivalirudin Product description


CAS No.: 128270-60-0

Molecular formula: c98h138n24o33

English synonyms: 128270-60-0; L-leucine, d-phenylalanyl-l-pro-lyl-l-l-arginyl-l-l-pro-lylycycycycycycycyl-l-l-asparacyl-l-l-asparacyl-l-l-phenylalanyl-l-l-phenylalanyl-l-l-l-l-phenylalanyl-l-l-l-phenylalanyl-l-l-l-phenylalanyl-l-pro-lyl-l-l-l-l-phenylalanyl-l-l-l-l-l-arginyl-l-l-l-l-l-l-l-l-l-l-l-l-l-l-l-l-l-l-l-l-l-l-l-l-l l-tyrosyl -; D-phenylalanyl-L-prolyl-L-arginyl-L-prolylglycylglycylglycylglycyl-L-asparaginylglycyl-L-alpha-aspartyl-L-phenylalanyl-L-alpha-glutamyl-L-alpha-glutamyl-L-isoleucyl-L-prolyl-L-alpha-glutamyl-L-alpha-glutamyl-L-tyrosyl-L-leucine

Molecular weight: 2180.2853

Sequence: d-phe-pro-arg-pro-gly-gly-gly-asn-gly-asp-phe-glu-ile-pro-glu-tyr-leu-oh

Use as an anticoagulant in patients with unstable angina undergoing percutaneous transluminal coronary angioplasty .

Bivalirudin is a synthetic 20 residue peptide (thrombin inhibitor) which reversibly inhibits thrombin. Once bound to the active site, thrombin cannot activate fibrinogen into fibrin, the crucial step in the formation of thrombus. It is administered intravenously.

Because it can cause blood stagnation, it is important to monitor changes in hematocrit, activated partial thromboplastin time, international normalized ratio and blood pressure.

    Bivalirudin Specifications

    CAS Registry Number128270-60-0
    CategoriesAPIsPeptides; Biopharmaceuticals
    Sales marketsWestern Europe; Asia; North America; Central/South America
    Supplied fromChina
    Selling PointsInternational Approvals/Standards

    Show more specifications

    CPhIonline

    Other Polypeptide APIs

    US-DMF LIST–Polypeptide APIs
    Product NameUS-DMF No.WC
    BivalirudinDMF 25531YES
    EptifibatideDMF 27651YES
    LiraglutideDMF 29302YES
    Icatibant AcetateDMF 28496YES
    Octreotide AcetateDMF 30249YES
    Teriparatide AcetateDMF 32144
    Ziconotide AcetateDMF 33139
    **

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