Chengdu Kaijie bio medicine Peptide API
Angiotensin Acetate Product description
Angiotensin II Acetate is the acetate salt form of therapeutic angiotensin II, a synthetic form of the endogenous angiotensin II, a peptide hormone of the renin-angiotensin-aldosterone system (RAAS) that causes vasoconstriction and an increase in blood pressure, that may be used for the treatment of septic or other distributive shock.
Upon administration, therapeutic angiotensin II binds to angiotensin II type 1 receptor on vascular smooth muscle cells which leads to Ca2+/calmodulin-dependent phosphorylation of myosin.
This causes smooth muscle contraction and results in vasoconstriction and an increase in blood pressure. Therapeutic angiotensin II also increases blood pressure by stimulating the release of the steroid hormone aldosterone, which regulates the renal absorption of water and sodium.
Angiotensin Acetate Chemical Properties
Giapreza is indicated for the treatment of refractory hypotension in adults with septic or other distributive shock who remain hypotensive despite adequate volume restitution and application of catecholamines and other available vasopressor therapies.,
| Molecular Formula | C52H75N13O14 |
|---|---|
| Synonyms | Angiotensin II acetate68521-88-0Angiotensin II human (acetate)Angiotensin II [USAN]Angiotensin II acetate (USAN)More… |
| Molecular Weight | 1106.2 g/mol |
| Parent Compound | CID 172198 (Angiotensin II) |
| Component Compounds | CID 172198 (Angiotensin II)CID 176 (Acetic acid) |
Polypeptide Production Specifications
| CAS Registry Number | 128270-60-0 |
|---|---|
| Categories | APIsPeptides; Biopharmaceuticals |
| Sales markets | Western Europe; Asia; North America; Central/South America |
| Supplied from | China |
| Selling Points | International Approvals/Standards |
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