Lanreotide Acetate

Lanreotide Acetate

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Lanreotide Acetate is the acetate salt of a synthetic cyclic octapeptide analogue of somatostatin. Lanreotide binds to somatostatin receptors (SSTR), specifically SSTR-2 and also to SSTR-5 with a lesser affinity.

However, compare with octreotide, this agent is less potent in inhibiting the release of growth hormone from the pituitary gland. Furthermore, lanreotide has an acute effect on decreasing circulating total and free insulin-like growth factor 1 (IGF-I).

This agent is usually given as a prolonged-release microparticle or Autogel formulation for the treatment of acromegaly and to relieve the symptoms of neuroendocrine tumors.

NCI Thesaurus (NCIt)
Lanreotide is a synthetic cyclic octapeptide analogue of somatostatin. Lanreotide binds to somatostatin receptors (SSTR), specifically SSTR-2 and also to SSTR-5 with a lesser affinity.

However, compare with octreotide, this agent is less potent in inhibiting the release of growth hormone from the pituitary gland. Furthermore, lanreotide has an acute effect on decreasing circulating total and free insulin-like growth factor 1 (IGF-I).

This agent is usually given as a prolonged-release microparticle or Autogel formulation for the treatment of acromegaly and to relieve the symptoms of neuroendocrine tumors.

NCI Thesaurus (NCIt)
Pasireotide is a synthetic polypeptide analogue of somatostatin that resembles the native hormone in its ability to suppress levels and activity of growth hormone, insulin, glucagon and many other gastrointestinal peptides.

Because its half-life is longer than somatostatin, pasireotide can be used clinically to treat neuroendocrine pituitary tumors that secrete excessive amounts of growth hormone causing acromegaly, or adrenocorticotropic hormone (ACTH) causing Cushing disease.

Pasireotide has many side effects including suppression of gall bladder contractility and bile production, and maintenance therapy can cause cholelithiasis and accompanying elevations in serum enzymes and bilirubin.

Lanreotide Acetate Structural Formula:

β-(2-Naphthyl)-D-Ala-Cys-Tyr-D-Trp-Lys-Val-Cys-Thr-NH2

Lanreotide Acetate Specifications

Synthesis mode	chemic synthesis，solid phase synthesis
Categories	APIsPeptides; Biopharmaceuticals；Polypeptide APIs
Sales markets	Western Europe; Asia; North America; Central/South America
Supplied from	China
Selling Points	International Approvals/Standards

Show more specificationsConsultation details

Other Polypeptide APIs

Chinese cGMP APIs
Product Name	GMP Certificate No.	WC
Levosimendan	SC20120022
Thymosin alpha1	SC20140047
Enfuvirtide	SC20140098
Octreotide Acetate	SC20150121	YES
Somatostatin	SC20150121
Thymopentin	SC20150121
Carbetocin	SC20160013
Atosiban	SC20170065

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