Liraglutide Product description
Diabetes mellitus, Liraglutide is a once-daily GLP-1 derivative for the treatment of type 2 diabetesLabel,2.
The prolonged action of liraglutide is achieved by attaching a fatty acid molecule at position 26 of the GLP-1 molecule, enabling it to bind reversibly to albumin within the subcutaneous tissue and bloodstream and be released slowly over timeLabel,2,3.
Binding with albumin results in slower degradation and reduced elimination of liraglutide from the circulation by the kidneys compared to GLP-12,3.
The effect of liraglutide is the increased secretion of insulin and decreased secretion of glucagon in response to glucose as well as slower gastric emptyingLabel. Liraglutide also does not adversely affect glucagon secretion in response to low blood sugar
Liraglutide Specifications
| CAS Registry Number | 204656-20-2 |
|---|---|
| Categories | APIsPeptides; Biopharmaceuticals |
| Sales markets | Western Europe; Middle East; North America; Central/South America |
| Supplied from | China |
| Selling Points | International Approvals/Standards |
Other Polypeptide APIs
| US-DMF LIST–Polypeptide APIs | ||
|---|---|---|
| Product Name | US-DMF No. | WC |
| Bivalirudin | DMF 25531 | YES |
| Eptifibatide | DMF 27651 | YES |
| Liraglutide | DMF 29302 | YES |
| Icatibant Acetate | DMF 28496 | YES |
| Octreotide Acetate | DMF 30249 | YES |
| Teriparatide Acetate | DMF 32144 | |
| Ziconotide Acetate | DMF 33139 | |
| * | * |
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