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Palmitoyl Pentapeptide-4
| INCI NAME： | Palmitoyl Pentapeptide-4 |
| Synonym： | Matrixyl, Palmitoyl Pentapeptide-3 |
| CAS No.： | 214047-00-4 |
| Peptide Sequence： | Pal-Lys-Thr-Thr-Lys-Ser-OH |
| MF.： | C39H75N7O10 |
| MW.： | 802 |
| Purity： | 98% |
| Grade： | Cosmetic |
| Packing（Powder）： | 500mg/bottle, 1g/bottle, 5g/bottle, 10g/bottle |
| Packing（Liquid）： | 0.1kg/bottle, 1kg/bottle, 5kg/bottle |
Company qualification
Goodie
ALSO-CALLED-LIKE-THIS: Matrixyl, Pal-KTTKS, Formerly Palmitoyl Pentapeptide-3
WHAT-IT-DOES: cell-communicating ingredient
Official CosIng Information
Details
A pretty famous and better-researched peptide consisting of five amino acids (the building blocks of all proteins). It was created in a joint effort by the French ingredient supplier, Sederma and the cosmetics industry big shot, Procter&Gamble.
The amino acid sequence of the peptide is lysine–threonine–threonine–lysine–serine (KTTKS). Sometimes, it’s also called collagen pentapeptide, as it’s a subfragment of skin-structure-giving type I collagen. The KTTKS amino sequence is then attached for better oil solubility and skin penetration to palmitic acid and BOOM; we get Palmitoyl Pentapeptide-4.
Though most research is manufacturer sponsored, the clinical studies about Palmitoyl Pentapeptide-4 are promising. In short, it can reduce fine lines, wrinkles and improve skin texture significantly (and at crazy low concentrations, the studies were done with just 3 ppm that is 0.0003%).
There are also studies comparing Palmitoyl Pentapeptide-4 with anti-aging gold standard, retinol. One of them compared 3ppm Pal-KTTKS with 700 ppm (0.07%) retinol and found that they showed similar wrinkle improving ability with the peptide showing better skin tolerability.
Bottom line, if you are into peptides, this is a good one to try.
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