“Peptide” acting on blood glucose concentration
The gut of human body is not only digestive organ, but also secretory organ. It can secrete glucagon like peptide-1 (GLP-1), which can stimulate islet cells to secrete insulin and regulate blood glucose. Moreover, its secretory effect on insulin has the characteristics of grape concentration dependence. It can only play a role when blood sugar is increased, and it will not lead to hypoglycemia.
But the “natural peptide” secreted by the human body will be hydrolyzed by the corresponding enzyme within a few minutes, and the action time is very short. Therefore, people have developed a “artificial peptide” similar to “natural peptide”, which can play the same role, but has higher enzyme stability, has a longer action time, and has the effect of reducing blood glucose.
Make people urine sugar increase “lie Jing”
Glucose for the human body is an important energy supply material, can not be easily wasted, so the human renal tubules will be the original urine glucose reabsorbed back to the blood, normal urine will not contain sugar. However, due to high blood sugar in diabetic patients, the glucose content in the original urine exceeds the absorption capacity of renal tubules, which will lead to sugar in the urine, which is also the origin of the name “diabetes”.
The “Lijing” drugs are sodium glucose cotransporter inhibitors (sglt2-i). In short, they can inhibit the renal tubular reabsorption of glucose, allowing more glucose to drain out of the urine, thus reducing the concentration of blood glucose. There is no need to worry about the increase of urine sugar caused by “Lijing”, because the main cause of diabetes damage to the body is hyperglycemia, which has little effect on the body.
Pay attention to the relationship between diabetes and cardiovascular disease
Diabetes mellitus can cause cell metabolism disorder, and then damage blood vessels and myocardial cells, causing related complications. Among them, the biggest threat to myocardial cells is the large vessel disease caused by diabetes, which causes coronary atherosclerosis. It is also because of this, so now the general view, diabetes as coronary heart disease “wait for the crisis.”.
Therefore, diabetic patients in hypoglycemic therapy, but also pay attention to the protection of cardiovascular. A number of clinical studies have shown that “peptide” and “Lijing” are two kinds of new hypoglycemic drugs, which can not only effectively reduce blood glucose, but also significantly reduce the risk of macrovascular complications in patients with type 2 diabetes.
However, the mechanism of cardiovascular protection of new hypoglycemic drugs has not been elucidated. Research shows that it may be the cumulative effect of multiple functions.
For example, “peptide” can inhibit oxidative activation and inflammatory reaction, inhibit myocardial fibrosis and plaque progress, and stabilize plaque;
while “Lijing” can improve myocardial metabolism, reduce body weight, increase lipid oxidation, change the ion content in myocardial cells, reduce blood pressure, reduce blood uric acid, and alleviate atherosclerosis.
In fact, from the study of new hypoglycemic drugs, we can see that the treatment of diabetes is not limited to the simple hypoglycemic effect, but to seek better protection of cardiovascular, in order to reduce the cardiovascular complications caused by diabetes, and help diabetic patients to obtain better quality of life.
In summary, “peptide” and “Lijing” are two new hypoglycemic drugs, which play a hypoglycemic effect in different ways, and at the same time, they also have protective effects on cardiovascular system. Hypoglycemic drugs can only be used under the guidance of doctors, and can not be used without authorization.
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